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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERBB4 All Species: 9.09
Human Site: Y1056 Identified Species: 20
UniProt: Q15303 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15303 NP_001036064.1 1308 146808 Y1056 G H S P P P A Y T P M S G N Q
Chimpanzee Pan troglodytes XP_516067 1308 146816 Y1056 G H S P P P A Y T P M S G N Q
Rhesus Macaque Macaca mulatta XP_001113953 1342 148045 L1048 P R G S Q S L L S P S S G Y M
Dog Lupus familis XP_545629 1251 140621 P1001 S P P P A Y T P M S G N Q F V
Cat Felis silvestris
Mouse Mus musculus Q61527 1292 145195 R1040 P I Y T S R T R I D S N R N Q
Rat Rattus norvegicus Q62956 1308 146940 Y1056 G H S P P P A Y T P M S G S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508590 1260 141049 P1010 D A E E Y L V P Q A F N I P P
Chicken Gallus gallus P13387 703 77409 Q453 A V V N L K I Q S L G L R S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001137223 1414 157718 G1161 I T A L D N P G Y H S T P D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04412 1426 159700 D1168 Q P E I C S L D I Y C T L L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P24348 1323 150493 C1063 I E I F S K H C Y T H A S D V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 48.2 93.5 N.A. 96.1 96.5 N.A. 88 27.5 N.A. 66 N.A. 35.6 N.A. 20.7 N.A.
Protein Similarity: 100 99.9 63.4 94.8 N.A. 97.7 98.4 N.A. 90.6 36.3 N.A. 76 N.A. 50.9 N.A. 37.5 N.A.
P-Site Identity: 100 100 20 6.6 N.A. 13.3 93.3 N.A. 0 0 N.A. 0 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 13.3 N.A. 20 100 N.A. 6.6 13.3 N.A. 26.6 N.A. 6.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 10 0 28 0 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 10 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 10 0 10 0 0 0 19 0 % D
% Glu: 0 10 19 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 10 0 0 10 0 % F
% Gly: 28 0 10 0 0 0 0 10 0 0 19 0 37 0 0 % G
% His: 0 28 0 0 0 0 10 0 0 10 10 0 0 0 0 % H
% Ile: 19 10 10 10 0 0 10 0 19 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 10 10 19 10 0 10 0 10 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 28 0 0 0 10 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 28 0 28 0 % N
% Pro: 19 19 10 37 28 28 10 19 0 37 0 0 10 10 10 % P
% Gln: 10 0 0 0 10 0 0 10 10 0 0 0 10 0 37 % Q
% Arg: 0 10 0 0 0 10 0 10 0 0 0 0 19 0 10 % R
% Ser: 10 0 28 10 19 19 0 0 19 10 28 37 10 19 10 % S
% Thr: 0 10 0 10 0 0 19 0 28 10 0 19 0 0 0 % T
% Val: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 0 28 19 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _